Multiple therapeutics have been authorized to treat COVID-19 for those who are at highest risk of severe illness from COVID-19. The Ohio Department of Health wants to ensure that all healthcare providers across Ohio are aware of the availability of COVID-19 treatment options, and to refer eligible patients to treatment locations as appropriate.

Currently available treatments include BebtelovimabPaxlovidMolnupiravir, and Evusheld.

These therapies require a prescription order from a licensed healthcare provider. Ohioans seeking any of these treatments must first reach out to their healthcare provider to discuss appropriate treatment options and a treatment plan.

Treatment Option Resources

Current Treatment Options

If you are an Ohio resident seeking more information about COVID-19 treatment and think you might qualify, please speak to your healthcare provider first and get a referral ito receive pre-exposure prophylaxis, monoclonal antibody treatment or oral antivirals.

Additional resources for healthcare providers:

Monoclonal Antibody Treatment

Monoclonal antibodies are laboratory-made proteins that mimic the immune system’s ability to fight off harmful antigens such as viruses. They are designed to block the virus’ attachment and entry into human cells.

What types of patients can benefit from treatment with monoclonal antibodies?

Patients may be eligible for treatment with monoclonal antibodies if they have experienced the onset of mild to moderate symptoms of COVID-19 in the last 10 days, have tested positive for COVID-19, and have one or more of the following high-risk factors

  • Are ≥65 years of age
  • Body mass index (BMI) ≥35
  • Chronic kidney disease
  • Diabetes
  • Immunosuppressive disease
  • Are currently receiving immunosuppressive treatment
  • Are ≥55 years of age AND have
    • cardiovascular disease, OR
    • hypertension, OR
    • chronic obstructive pulmonary disease/other chronic respiratory disease
  • Are 12 to 17 years of age AND have
    • BMI ≥85th percentile for their age and gender based on CDC growth charts, OR
    • sickle cell disease, OR – congenital or acquired heart disease, OR
    • neurodevelopmental disorders, for example, cerebral palsy, OR
    • a medical-related technological dependence, for example, tracheostomy, gastrostomy, or positive pressure ventilation (not related to COVID-19), OR
    • asthma, reactive airway, or other chronic respiratory disease that requires daily medication for control.

Download the High-Risk-COVID-19-Patients guide from

Once a high-risk individual is diagnosed, they need to know where they can go to get a monoclonal antibodies infusion. The two links below allow patients to search for infusion centers that are located closest to them in the state.